Tissue Microarray

Tissue Microarray Services

Tissue Microarray (TMA) technology can be employed for high throughput analysis of biomarker expression in a large number of tissue samples. The QLMP can provide free advice to investigators on TMA design. 

The QLMP has constructed hundreds of TMA blocks with tens of thousands of cores for investigator and Clinical Trials projects.  Cores have been harvested from a wide array of tissue tpes including prostate, breast, pancrease, lung, ovary, brain, head and neck, and many other disease sites.

Digital pathology instrumentation is avaialable for capturing high resolution digital images of TMA spots.  The images can be viewed online along with free tools for image annotation.  Software is available to perform automated quantitative image analysis on both bright field and immunofluorscent images.

For new TMA construction please contact us and arrange a meeting to discuss array design, construction, pricing, digital imaging and online access, image analysis, and data handling.

The QLMP is equipped with the 3DHistech fully automated tissue microarrayer.  Core size can be 0.6 mm, 1.0 mm, 1.5 mm, or 2.0 mm.  For 0.6 mm size a single TMA block can consist of over 400 cores.  A complete layout of TMA cores can be provided in excel format to researchers upon request.

We can provide expertise in the following services:

1)  TMA Design and Construction     
2)  TMA Block Sectioning     
3)  TMA Immunohistochemical Staining     
4)  TMA H&E Staining
5)  TMA High Resolution Slide Scan (20x and 40x)
6)  TMA Scanned Image Web Hosting

Click here to see TMA prices:  Fees