The Immunology of Factor VIII

Project Aims1.

1.1.To understand the mechanisms mediating immunogenic and tolerogenic responses to Factor VIII.

2. 1.2.To develop novel approaches to generate immunologic tolerance to Factor VIII.

 
Innate Immune Response


Induction of Immune Tolerance to FVIII



Factor VIII Antibody Response in Hemophilia A Mice




SPECIFIC AREAS OF RESEARCH ACTIVITY
Physiology and
Pathobiology of
von Willebrand Factor
The
Immunology
of Factor VIII
Gene Transfer
Approaches
for Hemophilia A